The paper deals with the two grape varieties– merlot and madrasa from the grape sites of the Ganja-Gazakh region of Azerbaijan. The determination of the residual amount of copper in these varieties was carried out in the laboratory of the Azerbaijan State Agricultural University. The qualitative determination of copper after using Cu (II) complexes, namely Cu-DNTA, synthesized from CuSO4.5H2O, nitro-substituted terephthalic acid, and N-donor ligands, based on the aforementioned factors and our experience with metal carboxylate by Atomic absorption spectroscopy according to the approved methods. Analyzes were performed on the Pin AAcle 500 Flame Atomic Absorption Spectrometer analyzer (PerkinElmer). The crystal structure of both compounds is determined by single crystal x-rays diffraction (SC-XRD) analysis which inferred that the coordination geometry is slightly distorted octahedral and square pyramidal in Cu-DNTA, respectively. The non-covalent interactions that are the main reason for the formation of the supramolecular assembly are explored by Hirsh feld surface analysis for both compounds and the propensity of each pair of chemical species to form crystal packing interactions is determined by enrichment ratio.