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VOL. 6, ISSUE 4 (2021)
Genomic sequence of worldwide strains of SARS-CoV-2: Insights the role of variants in disease epidemiology
Authors
Sudheer Menon
Abstract
In humans, the SARS-CoV-2 infection has achieved endemicity. This needs the creation of quick genetic monitoring technologies to supplement existing comprehensive, albeit slower, genome sequencing-based approaches. The study's main goal was to look into the genomic sequencing of SARS CoV-2 in order to learn more about its potential in global disease epidemiology. SARS-CoV-2 whole genome sequencing was performed on remnant samples from nasopharyngeal and oropharyngeal swabs taken from symptomatic patients. The produced sample was subjected to real-time PCR, and the resulting sequences were then symmetrized to create a dataset. This data was subsequently integrated into global datasets available on several websites, including the GISAID and ViPR. It was also intended to investigate the distribution pattern of distinct SARS-CoV-2 strains. Epidemiological study and the method of estimating reproductive numbers were used to achieve this goal. The findings revealed that genome sequencing is closely linked to the disease epidemiology of distinct SARS-CoV-2 strains. These strains tend to decrease with the passage of time and their distribution was disturbed geographically due to the invention of vaccines.
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Pages:14-21
How to cite this article:
Sudheer Menon "Genomic sequence of worldwide strains of SARS-CoV-2: Insights the role of variants in disease epidemiology ". International Journal of Advanced Research and Development, Vol 6, Issue 4, 2021, Pages 14-21
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