This paper explain how to use Orthogonal Space Time Block code (OSTBC) in Multiple Input Multiple Output (MIMO) system with different antenna configurations to improve the performance by maximizing diversity gain. Also investigates the fading and distortion caused by the noise channel. The proposed methodology to reduce the channel effect to get a reliable data transfer is based on encoding the signal at the transmitter then using the error detection and correction algorithms in the receiver to recover the data sent through the channel. To estimate this performance. The bit error rate will be measured and the results will show the optimization in error reduction with different values of signal to noise ratio.