This essay endeavour to encapsulate the historic journey of the Portuguese navigator Vasco da Gama and the Portuguese commercial and imperial ambitions carried out on the Malabar Coast. The Portuguese being the pioneering European trading company to set foot in India also had noticeable interventions made in the spheres of politics besides trade. Having realized the vitality of the political patronage for acquiring merchandize, they have managed to win the support of the native principalities, though not all, often putting one against the other. However it is to be noted that it was the Portuguese much before anybody else who did bring politics, rather say, violence into the Indian Ocean trade. This essay deals with the trading fortunes and the political interventions of the Portuguese on the Malabar Coast.