There are various neurotransmitters which help to enhance learning and memory these are serotonin, dopamine, acetycholine etc. These neurotransmitters are derived from their precursors. The precursor of neurotransmitters are the active compound or nutrients which is found in various food products. Inspite of these there are various cofactor of particular neurotransmitter. These cofactor are also vitamins and minerals for example- cofactor of serotonin is zinc, iron, vitamin C, vitamin E, manganese etc. The cofactor of acetylcholine is vitamin B5, alpha lipoic acid & cofactor of dopamine is vitamin B6 & iron. These cofactor or nutrients of particular neurotransmitters have their respective enhancer which is also nutrient example- zinc is cofactor of serotonin whereas vitamin A is enhancer of zinc. Every nutrient have their particular peak & t ½ value as medicine. So there is need to plan such type of dietary pattern to patients to enhance learning through their respective cofactor with enhancer & there is also need to give enhancer before co factor peak & t ½ level will attain.