A stroke or Cerebro Vascular Accident (CVA) is when Blood flow to a part of your brain is stopped either by a blockage or the rupture of a Blood vessel. Stroke is the third common cause of death in the world after coronary heart disease and cancer especially in the elderly. Stroke also causes secondary medical problems, including dementia, depression, epilepsy, falls and fractures. Strokes are two main types’ Ischemic stroke and Hemorrhagic stroke. An ischemic stroke is the most common and occurs when a blood clot blocks a blood vessel and prevents blood and oxygen from getting to a part of the brain. There are two ways that this can happen. One way is an embolic stroke, and other way is a thrombotic stroke. The hemorrhage may occur in any blood vessel in the brain, or it may occur in the membrane surrounding the brain. Magnesium is a natural calcium antagonist and modulates vasomotor tone, blood pressure, and peripheral blood flow. Magnesium is thought to have the ability to prevent glutamate from causing food calcium in the cells. Patients with high serum uric acid levels had a significant increased risk of poor outcome. Increased UA levels were found to be associated with increased risk of ischemic as well as hemorrhagic strokes. Control of risk factors could significantly reduce the incidence of stroke. Non modifiable risk markers for ischemic stroke include age, sex, family history and race. Modifiable risk markers for ischemic stroke include hypertension, cardiac disease, diabetes mellitus, hyperlipidemia, cigarette smoking, alcohol abuse, physical inactivity, transient ischemic attack. Improved detection, modification or control of risk factors could reduce the incidence of stroke and reduce the impact of this disease.